ABCA4 Antikörper

Produktnummer ABIN6566982

Der Kaninchen Polyklonal Anti-ABCA4-Antikörper wurde für WB validiert. Er ist geeignet, ABCA4 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für ABCA4 Antikörper (ABIN6566982)

Target: ABCA4 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABCA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ABCA4 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human ABCA4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ABCA4

Target: ABCA4 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4))

Andere Bezeichnung: ABCA4

Hintergrund:

Synonyms: ABC 10,ABC A4,ABC transporter,retinal-specific,ABC10,ABCA 4,abcA4,ABCA4,ABCR,ARMD 2,ARMD2,ATP binding cassette 10,ATP binding cassette sub family A member 4,ATP binding cassette sub family A member4,ATP binding cassette transporter,ATP binding cassette transporter retinal specific,ATP binding cassette,sub family A (ABC1),member 4,ATP binding cassette,sub family A (ABC1),member4,ATP binding cassette10,ATP binding transporter,retina specific,ATP-binding cassette sub-family A member 4,CORD 3,CORD3,DKFZp781N1972,FFM,FLJ17534,Photoreceptor rim protein,Retina specific ABC transporter,Retinal specific ATP binding cassette transporter,Retinal-specific ATP-binding cassette transporter,RIM ABC transporter,RIM protein,RmP,RP 19,RP19,Stargardt disease protein,STGD,STGD1

Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2.

Molekulargewicht:

Observed_MW: 256kDa

Calculated_MW: 255kDa

Gen-ID: 24

UniProt: P78363