RASGRP1 Antikörper
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- Target Alle RASGRP1 Antikörper anzeigen
- RASGRP1 (RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RASGRP1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein of human RASGRP1
- Isotyp
- IgG
- Top Product
- Discover our top product RASGRP1 Primärantikörper
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- Applikationshinweise
- WB 1:1000 - 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- RASGRP1 (RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1))
- Andere Bezeichnung
- RASGRP1 (RASGRP1 Produkte)
- Synonyme
- Rasgrp antikoerper, CALDAG-GEFI antikoerper, CALDAG-GEFII antikoerper, RASGRP antikoerper, V antikoerper, hRasGRP1 antikoerper, RAS guanyl releasing protein 1 antikoerper, Rasgrp1 antikoerper, RASGRP1 antikoerper
- Hintergrund
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Synonyms: Calcium and DAG-regulated guanine nucleotide exchange factor II,CALDAG-GEFI,CalDAG-GEFII,GRP1,Guanine nucleotide exchange factor, calcium and DAG regulated, Rap1A,hRasGRP1,Ras activator RasGRP,RAS guanyl nucleotide releasing protein 1,RAS guanyl releasing protein 1 (calcium and DAG-regulated),RAS guanyl releasing protein 1,RAS guanyl-releasing protein 1,Ras guanyl-releasing protein,RASGRP,rasgrp1,V
Background: This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE).
- Molekulargewicht
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Observed_MW: 90kDa
Calculated_MW: 55kDa/62kDa/68kDa/86kDa/90kDa
- Gen-ID
- 10125
- UniProt
- O95267
- Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung
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