LMAN1 Antikörper

Produktnummer ABIN6566931

Der Kaninchen-Polyklonal Anti-LMAN1-Antikörper wurde für WB validiert. Er ist geeignet zum Nachweis von LMAN1 in Proben aus Human, Maus und Ratte. }

Kurzübersicht für LMAN1 Antikörper (ABIN6566931)

Target: LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LMAN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-LMAN1 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human LMAN1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu LMAN1

Target: LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

Andere Bezeichnung: LMAN1

Hintergrund:

Synonyms: Endoplasmic reticulum golgi intermediate compartment protein 53 ,ER-Golgi intermediate compartment 53 kDa protein,ERGIC-53,ERGIC53,ERGIC53 like protein,F5F8D,FMFD1,Gp58,Intracellular mannose specific lectin ,Intracellular mannose-specific lectin MR60,Lectin mannose binding 1 ,Lectin mannose-binding 1,Lman1,LMAN1 like protein ,LMAN1,MCFD1,MR60,Protein ERGIC-53

Background: The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi, functioning as a cargo receptor for glycoprotein transport. The protein has an N-terminal signal sequence, a calcium-dependent and  pH -sensitive carbohydrate recognition domain, a stalk region that functions in oligomerization, a transmembrane domain, and a short cytoplasmic domain required for organelle targeting. Allelic variants of this gene are associated with the autosomal recessive disorder combined factor V-factor VIII deficiency.

Molekulargewicht:

Observed_MW: 55kDa

Calculated_MW: 57kDa

Gen-ID: 3998

UniProt: P49257