STAR Antikörper (Steroidogenic Acute Regulatory Protein)

Details for Product anti-STAR Antibody No. ABIN6566888
Target
Reaktivität
Human, Maus
53
13
12
1
Wirt
Kaninchen
46
7
Klonalität
Polyklonal
Konjugat
Dieser STAR Antikörper ist unkonjugiert
6
4
3
3
3
2
2
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
34
25
14
6
6
4
4
4
3
2
2
1
1
1
1
Optionen
Immunogen Recombinant protein of human STAR
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung STAR (STAR Antibody Abstract)
Hintergrund

Synonyms: Cholesterol trafficker,Luteinizing hormone induced protein,mitochondrial,Mitochondrial steroid acute regulatory protein,StAR,StAR related lipid transfer (START) domain containing 1,STAR,StARD1,START domain containing 1,START domain containing protein 1,START domain-containing protein 1,Steroid acute regulatory protein,Steroidogenic acute regulator,Steroidogenic acute regulatory protein,Steroidogenic acute regulatory protein mitochondrial

Background: The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13.

Molekulargewicht

Observed_MW: 35kDa

Calculated_MW: 31kDa

Gen-ID 6770
UniProt P49675
Pathways Metabolism of Steroid Hormones and Vitamin D, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis
Applikations-hinweise WB 1:500 - 1:2000 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Steroidogenic Acute Regulatory Protein (STAR) antibody (ABIN6566888) Immunofluorescence analysis of U2OS cells using STAR antibody.
Image no. 2 for anti-Steroidogenic Acute Regulatory Protein (STAR) antibody (ABIN6566888) Western blot analysis of extracts of various cell lines, using STAR antibody.