Synonyms: A530094C12Rik,AI451642,AVIEF,B cell scaffold protein with ankyrin repeats 1,BANK,FLJ20706,FLJ34204
Background: The protein encoded by this gene is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. This protein can also promote Lyn-mediated tyrosine phosphorylation of inositol 1,4,5-trisphosphate receptors. Polymorphisms in this gene are associated with susceptibility to systemic lupus erythematosus. Alternative splicing results in multiple transcript variants.