KIF14 Antikörper

Produktnummer ABIN6566849

Dieses Anti-KIF14-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von KIF14 in IHC und IF. Geeignet für Human, Maus und Ratte.

Kurzübersicht für KIF14 Antikörper (ABIN6566849)

Target: KIF14 (Kinesin Family Member 14 (KIF14))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIF14 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-KIF14 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human KIF14 (NP_055690.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu KIF14

Target: KIF14 (Kinesin Family Member 14 (KIF14))

Andere Bezeichnung: KIF14

Hintergrund: This gene encodes a member of the kinesin-3 superfamily of microtubule motor proteins. These proteins are involved in numerous processes including vesicle transport, chromosome segregation, mitotic spindle formation, and cytokinesis. In human HeLa-S3 and 293T cells, this protein is localized to the cytoplasm during interphase, to the spindle poles and spindle microtubules during mitosis, and to the midbody during cytokinesis. An internal motor domain displays microtubule-dependent ATPase activity, consistent with its function as a microtubule motor protein. Knockdown of this gene results in failed cytokinesis with endoreplication, which results in multinucleated cells. This gene has been identified as a likely oncogene in breast, lung and ovarian cancers, as well as retinoblastomas and gliomas. Alternative splicing results in multiple transcript variants.

Molekulargewicht:

Observed_MW: 190kDa

Calculated_MW: 186kDa

Gen-ID: 9928

UniProt: Q15058