LOXL1 Antikörper

Produktnummer ABIN6566806

Der Kaninchen Polyklonal Anti-LOXL1-Antikörper wurde für IF validiert. Er ist geeignet, LOXL1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für LOXL1 Antikörper (ABIN6566806)

Target: LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LOXL1 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF)

Produktdetails anti-LOXL1 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human LOXL1 (NP_005567.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu LOXL1

Target: LOXL1 (Lysyl Oxidase-Like 1 (LOXL1))

Andere Bezeichnung: LOXL1

Hintergrund: This gene encodes a member of the lysyl oxidase family of proteins. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin. The encoded preproprotein is proteolytically processed to generate the mature enzyme. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Mutations in this gene are associated with exfoliation syndrome.

Molekulargewicht:

Observed_MW: 80kDa

Calculated_MW: 63kDa

Gen-ID: 4016

UniProt: Q08397