HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) Antikörper

Produktnummer ABIN6566799

Der Kaninchen Polyklonal Anti--Antikörper wurde für WB validiert. Er ist geeignet, in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) Antikörper (ABIN6566799)

Target: HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human ERVFRD-1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000 - 1:4000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Antigendetails

Target: HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)

Andere Bezeichnung: ERVFRD-1

Hintergrund:

Synonyms: Endogenous Retrovirus Group FRD Member 1 Envelope,Endogenous Retrovirus Group FRD Member 1,HERV-FRD_6p24.1 Provirus Ancestral Env Polyprotein,Envelope Polyprotein,ERVFRDE1,HERV-FRD,HERV-FRD Provirus Ancestral Env Polyprotein,Endogenous Retrovirus Group FRD, Member 1,Syncytin 2,HERV-W/FRD,Syncytin-2,GLLL6191,UNQ6191,EnvFRD

Background: Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of a human endogenous retrovirus provirus on chromosome 6 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.

Molekulargewicht:

Observed_MW: 38kDa

Calculated_MW: 59kDa

Gen-ID: 405754

UniProt: P60508