Dystroglycan Antikörper

Produktnummer ABIN6566766

Produktdetails anti-Dystroglycan Antikörper

Target: Dystroglycan (DAG1) (Dystroglycan 1 (DAG1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dystroglycan Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human DAG1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Dystroglycan

Target: Dystroglycan (DAG1) (Dystroglycan 1 (DAG1))

Andere Bezeichnung: DAG1 (DAG1 Produkte)

Hintergrund:

Synonyms: 156DAG,A3a,AGRNR,Alpha dystroglycan,Alpha-DG,Beta-DG,Beta-dystroglycan,DAG,Dag1,DAG1,Dystroglycan 1 (dystrophin associated glycoprotein 1),Dystroglycan,Dystrophin associated glycoprotein 1,Dystrophin-associated glycoprotein 1,OTTHUMP00000210857,OTTHUMP00000210858

Background: This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein.

Molekulargewicht:

Observed_MW: 97kDa

Calculated_MW: 97kDa

Gen-ID: 1605

UniProt: Q14118

Pathways: Maintenance of Protein Location, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus