Stabilin 2 (STAB2) Antikörper

Details zu Produkt Nr. ABIN6566765
Target
Reaktivität
Human, Maus, Ratte
25
17
17
Wirt
Kaninchen
19
5
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
13
6
5
3
3
Optionen
Immunogen Recombinant protein of human STAB2
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung STAB2 (STAB2 Antibody Abstract)
Hintergrund

Synonyms: 190 kDa form stabilin-2,190 kDa hyaluronan receptor for endocytosis,EGF-like,FAS1 EGF-like and X-link domain-containing adhesion molecule 2,Fasciclin,FEEL-2,FEEL2,FELL,FEX2,HARE,Hyaluronan receptor for endocytosis,laminin-type EGF-like and link domain-containing scavenger receptor 2,link domain-containing scavenger receptor 2,STAB-2,Stab2,STAB2

Background: This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes.

Molekulargewicht

Observed_MW: 277kDa

Calculated_MW: 276kDa

Gen-ID 55576
UniProt Q8WWQ8
Pathways Glycosaminoglycan Metabolic Process
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Stabilin 2 (STAB2) antibody (ABIN6566765) Western blot analysis of extracts of various cell lines, using STAB2 antibody.