Stabilin 2 (STAB2) Antikörper

Produktnummer ABIN6566765

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch in WB. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für Stabilin 2 (STAB2) Antikörper (ABIN6566765)

Target: Stabilin 2 (STAB2)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human STAB2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Antigendetails

Target: Stabilin 2 (STAB2)

Andere Bezeichnung: STAB2

Hintergrund:

Synonyms: 190 kDa form stabilin-2,190 kDa hyaluronan receptor for endocytosis,EGF-like,FAS1 EGF-like and X-link domain-containing adhesion molecule 2,Fasciclin,FEEL-2,FEEL2,FELL,FEX2,HARE,Hyaluronan receptor for endocytosis,laminin-type EGF-like and link domain-containing scavenger receptor 2,link domain-containing scavenger receptor 2,STAB-2,Stab2,STAB2

Background: This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes.

Molekulargewicht:

Observed_MW: 277kDa

Calculated_MW: 276kDa

Gen-ID: 55576

UniProt: Q8WWQ8

Pathways: Glycosaminoglycan Metabolic Process