Neuregulin 1 Antikörper

Produktnummer ABIN6566642

Der Kaninchen Polyklonal Anti-Neuregulin 1-Antikörper wurde für WB validiert. Er ist geeignet, Neuregulin 1 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für Neuregulin 1 Antikörper (ABIN6566642)

Target: Neuregulin 1 (NRG1)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Neuregulin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Neuregulin 1 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human NRG1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Neuregulin 1

Target: Neuregulin 1 (NRG1)

Andere Bezeichnung: NRG1

Hintergrund:

Synonyms: Acetylcholine receptor-inducing activity,Acetylcholine receptor-inducing activity,CHICK,homolog of,ARIA,Breast cancer cell differentiation factor p45,GGF,GGF2,Glial growth factor,Heregulin,heregulin,alpha (45kD,ERBB2 p185-activator),HGL,HRG,HRG1,HRGA,MST131,NDF,Neu differentiation factor,Neuregulin 1,neuregulin 1 type IV beta 1a,neuregulin 1 type IV beta 3,Neuregulin-1,NRG 1,nrg1,NRG1-IT2,NRG1,OTTHUMP00000225398,OTTHUMP00000225419,OTTHUMP00000225420,OTTHUMP00000225421,OTTHUMP00000225422,OTTHUMP00000225477,OTTHUMP00000225545,OTTHUMP00000230603,OTTHUMP00000230605,pro-neuregulin-1,membrane-bound isoform,Pro-NRG1,ProNRG1,Sensory and motor neuron-derived factor,SMDF

Background: The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).

Molekulargewicht:

Observed_MW: 70kDa

Calculated_MW: 26kDa/31kDa/45- 50kDa/65-71kDa

Gen-ID: 3084

UniProt: Q02297

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation