TJP2 Antikörper (Tight Junction Protein 2 (Zona Occludens 2))

Details for Product anti-TJP2 Antibody No. ABIN6566621
Target
Reaktivität
Human, Maus, Ratte
80
20
19
10
3
3
3
3
2
1
1
1
Wirt
Kaninchen
75
5
2
Klonalität
Polyklonal
Konjugat
Dieser TJP2 Antikörper ist unkonjugiert
5
4
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
54
34
13
10
9
9
7
6
5
2
1
Optionen
Immunogen Recombinant protein of human TJP2
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung TJP2 (TJP2 Antibody Abstract)
Hintergrund

Synonyms: C9DUPq21.11,DFNA51,DUP9q21.11,Friedreich ataxia region gene X104 (tight junction protein ZO-2),MGC26306 ,PFIC4,Tight junction protein 2,Tight junction protein ZO 2,Tight junction protein ZO-2,TJP2,X104,ZO 2,ZO-2,ZO2,ZO2,Zona occludens 2,Zona occludens protein 2,Zonula occludens protein 2

Background: This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.

Molekulargewicht

Observed_MW: 160kDa

Calculated_MW: 111-137kDa

Gen-ID 9414
UniProt Q9UDY2
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Tight Junction Protein 2 (Zona Occludens 2) (TJP2) antibody (ABIN6566621) Immunohistochemistry of paraffin-embedded human lung cancer using TJP2 antibody.
Image no. 2 for anti-Tight Junction Protein 2 (Zona Occludens 2) (TJP2) antibody (ABIN6566621) Western blot analysis of extracts of various cell lines, using TJP2 antibody.
Image no. 3 for anti-Tight Junction Protein 2 (Zona Occludens 2) (TJP2) antibody (ABIN6566621) Immunohistochemistry of paraffin-embedded rat spleen using TJP2 antibody.