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PKN1 Antikörper

PKN1 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6566611
  • Target Alle PKN1 Antikörper anzeigen
    PKN1 (Protein Kinase N1 (PKN1))
    Reaktivität
    • 34
    • 8
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 22
    • 12
    Kaninchen
    Klonalität
    • 23
    • 11
    Polyklonal
    Konjugat
    • 20
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser PKN1 Antikörper ist unkonjugiert
    Applikation
    • 19
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein of human PKN1
    Isotyp
    IgG
    Top Product
    Discover our top product PKN1 Primärantikörper
  • Applikationshinweise
    WB 1:500 - 1:1000 IHC 1:50 - 1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PKN1 (Protein Kinase N1 (PKN1))
    Andere Bezeichnung
    PKN1 (PKN1 Produkte)
    Hintergrund

    Synonyms: DBK,DPKN,PAK 1,PRK 1,PROTEIN KINASE C RELATED KINASE 1,SERINE/THREONINE PROTEIN KINASE N

    Background: The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

    Molekulargewicht

    Observed_MW: 120kDa

    Calculated_MW: 104kDa

    Gen-ID
    5585
    UniProt
    Q16512
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