PKN1 Antikörper
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- Target Alle PKN1 Antikörper anzeigen
- PKN1 (Protein Kinase N1 (PKN1))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PKN1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein of human PKN1
- Isotyp
- IgG
- Top Product
- Discover our top product PKN1 Primärantikörper
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- Applikationshinweise
- WB 1:500 - 1:1000 IHC 1:50 - 1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PKN1 (Protein Kinase N1 (PKN1))
- Andere Bezeichnung
- PKN1 (PKN1 Produkte)
- Hintergrund
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Synonyms: DBK,DPKN,PAK 1,PRK 1,PROTEIN KINASE C RELATED KINASE 1,SERINE/THREONINE PROTEIN KINASE N
Background: The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
- Molekulargewicht
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Observed_MW: 120kDa
Calculated_MW: 104kDa
- Gen-ID
- 5585
- UniProt
- Q16512
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