alpha Fetoprotein Antikörper (alpha-Fetoprotein)

Details for Product anti-AFP Antibody No. ABIN6566493
Target
Reaktivität
Human, Maus, Ratte
343
59
39
36
33
25
7
5
4
3
3
2
2
1
1
Wirt
Kaninchen
216
166
14
5
2
1
Klonalität
Polyklonal
Konjugat
Dieser alpha Fetoprotein Antikörper ist unkonjugiert
43
30
20
11
10
8
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
Applikation
Immunofluorescence (IF), Western Blotting (WB)
184
172
115
92
81
49
43
38
36
24
21
21
17
12
10
6
6
4
4
4
4
3
3
2
2
2
1
1
1
1
1
1
1
Optionen
Immunogen A synthetic peptide of human AFP
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung AFP (AFP Antibody Abstract)
Hintergrund

Synonyms: Afp,AFPD,Alpha fetoglobulin,Alpha fetoprotein,Alpha fetoprotein precursor,Alpha-1-fetoprotein,Alpha-fetoglobulin,Alpha-fetoprotein,alpha-fetoprotein,Hereditary persistence of,included,FETA,FETA,Hereditary persistence of alpha fetoprotein,HPAFP

Background: This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Molekulargewicht

Observed_MW: 65kDa

Calculated_MW: 68kDa

Gen-ID 174
UniProt P02771
Pathways C21-Steroid Hormone Metabolic Process
Applikations-hinweise WB 1:500 - 1:2000 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-alpha-Fetoprotein (AFP) antibody (ABIN6566493) Western blot analysis of extracts of various cell lines, using AFP antibody.
Image no. 2 for anti-alpha-Fetoprotein (AFP) antibody (ABIN6566493) Immunofluorescence analysis of HeLa cells using AFP antibody.