FBLIM1 Antikörper (C-Term)

Produktnummer ABIN656647

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch FBLIM1 in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für FBLIM1 Antikörper (C-Term) (ABIN656647)

Target: FBLIM1 (Filamin Binding LIM Protein 1 (FBLIM1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBLIM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB32318

Produktdetails anti-FBLIM1 Antikörper

Bindungsspezifität: AA 294-323, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FBLIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 294-323 amino acids from the C-terminal region of human FBLIM1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: FBLIM1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu FBLIM1

Target: FBLIM1 (Filamin Binding LIM Protein 1 (FBLIM1))

Andere Bezeichnung: FBLIM1

Hintergrund: This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht: 40670

Gen-ID: 54751

NCBI Accession: NP_001019386, NP_001019387, NP_060026

UniProt: Q8WUP2