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PCDHA7 Antikörper (AA 272-300)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PCDHA7 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN656584

Kurzübersicht für PCDHA7 Antikörper (AA 272-300) (ABIN656584)

Target

Alle PCDHA7 Antikörper anzeigen
PCDHA7 (Protocadherin alpha 7 (PCDHA7))

Reaktivität

Human

Wirt

  • 8
  • 2
Kaninchen

Klonalität

  • 8
  • 2
Polyklonal

Konjugat

  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser PCDHA7 Antikörper ist unkonjugiert

Applikation

  • 10
  • 9
  • 7
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

RB30194
  • Bindungsspezifität

    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 272-300

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This PCDHA7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-300 amino acids from the Central region of human PCDHA7.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000. IHC-P: 1:10~50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    PCDHA7 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    Haltbarkeit

    6 months
  • Target

    PCDHA7 (Protocadherin alpha 7 (PCDHA7))

    Andere Bezeichnung

    PCDHA7

    Hintergrund

    This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

    Molekulargewicht

    100865

    Gen-ID

    56141

    NCBI Accession

    NP_061733, NP_114040

    UniProt

    Q9UN72
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