CYP2S1 Antikörper (C-Term)

Produktnummer ABIN656566

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CYP2S1 in WB, IF und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für CYP2S1 Antikörper (C-Term) (ABIN656566)

Target: CYP2S1 (Cytochrome P450, Family 2, Subfamily S, Polypeptide 1 (CYP2S1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP2S1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB17020

Produktdetails anti-CYP2S1 Antikörper

Bindungsspezifität: AA 399-428, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CYP2S1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-428 amino acids from the C-terminal region of human CYP2S1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-CYP2S1 Antikörper (ABIN656566)

Yang, Zhou, Li, Tong, Sun, Qing, Sun, Yang, Hu, Jiang, Yan, He, Wan: "Upregulation of CYP2S1 by oxaliplatin is associated with p53 status in colorectal cancer cell lines." in: Scientific reports, Vol. 6, pp. 33078, (2016) (PubMed).

Yang, Li, Li, Tong, Hu, Yang, Yan, He, Wan: "CYP2S1 depletion enhances colorectal cell proliferation is associated with PGE2-mediated activation of ?-catenin signaling." in: Experimental cell research, Vol. 331, Issue 2, pp. 377-86, (2015) (PubMed).

Details zu CYP2S1

Target: CYP2S1 (Cytochrome P450, Family 2, Subfamily S, Polypeptide 1 (CYP2S1))

Andere Bezeichnung: CYP2S1

Hintergrund: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens, however, the specific function of the human protein has not been determined.

Molekulargewicht: 55817

Gen-ID: 29785

NCBI Accession: NP_085125

UniProt: Q96SQ9