UGDH Antikörper (C-Term)

Produktnummer ABIN656544

Dieses Anti-UGDH-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von UGDH in WB und IHC (p). Geeignet für Human.

Kurzübersicht für UGDH Antikörper (C-Term) (ABIN656544)

Target: UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UGDH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB32083

Produktdetails anti-UGDH Antikörper

Bindungsspezifität: AA 465-494, C-Term

Homologie: M, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This UGDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 465-494 amino acids from the C-terminal region of human UGDH.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: UGDH Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu UGDH

Target: UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))

Andere Bezeichnung: UGDH

Hintergrund: The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 55024

Gen-ID: 7358

NCBI Accession: NP_001171629, NP_001171630, NP_003350

UniProt: O60701

Pathways: Glycosaminoglycan Metabolic Process