Calpain 6 Antikörper (AA 390-419)

Produktnummer ABIN656477

Der Kaninchen Polyklonal Anti-Calpain 6-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, Calpain 6 in Proben von Human zu detektieren.

Kurzübersicht für Calpain 6 Antikörper (AA 390-419) (ABIN656477)

Target: Calpain 6 (CAPN6)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calpain 6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB19561

Produktdetails anti-Calpain 6 Antikörper

Bindungsspezifität: AA 390-419

Homologie: M, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CAPN6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 390-419 amino acids from the Central region of human CAPN6.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: CAPN6 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu Calpain 6

Target: Calpain 6 (CAPN6)

Andere Bezeichnung: CAPN6

Hintergrund: Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.

Molekulargewicht: 74576

Gen-ID: 827

NCBI Accession: NP_055104

UniProt: Q9Y6Q1