PCDHGC5 Antikörper (AA 499-526)

Produktnummer ABIN656266

Produktdetails anti-PCDHGC5 Antikörper

Target: PCDHGC5 (Protocadherin gamma Subfamily C, 5 (PCDHGC5))

Bindungsspezifität: AA 499-526

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDHGC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PCDHGC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 499-526 amino acids from the Central region of human PCDHGC5.

Klon: RB31976

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: PCDHGC5 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu PCDHGC5

Target: PCDHGC5 (Protocadherin gamma Subfamily C, 5 (PCDHGC5))

Andere Bezeichnung: PCDHGC5 (PCDHGC5 Produkte)

Synonyme: PCDH-GAMMA-C5 antikoerper, protocadherin gamma subfamily C, 5 antikoerper, PCDHGC5 antikoerper, Pcdhgc5 antikoerper

Hintergrund: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Molekulargewicht: 101921

Gen-ID: 56097

NCBI Accession: NP_061752, NP_115783

UniProt: Q9Y5F6