Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FADS2 in WB, FACS, IHC (p) und IF. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This FADS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-108 amino acids from the N-terminal region of human FADS2.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
FADS2 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Haltbarkeit
6 months
Simón, Agnolazza, German, Garelli, Politi, Agbaga, Anderson, Rotstein: "Synthesis of docosahexaenoic acid from eicosapentaenoic acid in retina neurons protects photoreceptors from oxidative stress." in: Journal of neurochemistry, Vol. 136, Issue 5, pp. 931-46, (2016) (PubMed).
Target
FADS2
(Fatty Acid Desaturase 2 (FADS2))
Andere Bezeichnung
FADS2
Hintergrund
The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1, this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.