KAT2B Antikörper (C-Term)

Produktnummer ABIN656013

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-KAT2B Antikörper (Klon RB14386) (ABIN656013) detektiert spezifisch KAT2B in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für KAT2B Antikörper (C-Term) (ABIN656013)

Target: KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KAT2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB14386

Produktdetails anti-KAT2B Antikörper

Bindungsspezifität: AA 802-832, C-Term

Homologie: M

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This PCAF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 802-832 amino acids from the C-terminal region of human PCAF.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-KAT2B Antikörper (ABIN656013)

Xiong, Svingen, Sarmento, Smyrk, Dave, Khanna, Lomberk, Urrutia, Faubion: "Differential coupling of KLF10 to Sin3-HDAC and PCAF regulates the inducibility of the FOXP3 gene." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 307, Issue 6, pp. R608-20, (2014) (PubMed).

Details zu KAT2B

Target: KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))

Andere Bezeichnung: PCAF

Hintergrund: CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.

Molekulargewicht: 93013

Gen-ID: 8850

NCBI Accession: NP_003875

UniProt: Q92831

Pathways: p53 Signalweg, Regulation of Carbohydrate Metabolic Process