PCDHA5 Antikörper (AA 287-315)

Produktnummer ABIN655942

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PCDHA5 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PCDHA5 Antikörper (AA 287-315) (ABIN655942)

Target: PCDHA5 (Protocadherin alpha 5 (PCDHA5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDHA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB31607

Produktdetails anti-PCDHA5 Antikörper

Bindungsspezifität: AA 287-315

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PCDHA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 287-315 amino acids from the Central region of human PCDHA5.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu PCDHA5

Target: PCDHA5 (Protocadherin alpha 5 (PCDHA5))

Andere Bezeichnung: PCDHA5

Hintergrund: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Molekulargewicht: 102048

Gen-ID: 56143

NCBI Accession: NP_061731, NP_113689

UniProt: Q9Y5H7