Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Klon
RB20555
Bindungsspezifität
AA 1025-1053, C-Term
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This ITGA8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1025-1053 amino acids from the C-terminal region of human ITGA8.
ITGA8
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
WB: 1:2000. WB: 1:2000. IHC-P: 1:50~100
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Target
ITGA8
(Integrin alpha-8 (ITGA8))
Andere Bezeichnung
ITGA8
Hintergrund
Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons.