NRP2 Antikörper (C-Term)

Produktnummer ABIN655525

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch NRP2 in WB. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für NRP2 Antikörper (C-Term) (ABIN655525)

Target: NRP2 (Neuropilin 2 (NRP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NRP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB19998

Produktdetails anti-NRP2 Antikörper

Bindungsspezifität: AA 798-827, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Neuropilin-2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 798-827 amino acids from the C-terminal region of human Neuropilin-2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-NRP2 Antikörper (ABIN655525)

Zhao, Fu, Yao, Jia, Zhang, Li, Dong, Gao, Liu, Chen, Zhou: "Label-free quantitative proteomic analysis of benzo(a)pyrene-transformed 16HBE cells serum-free culture supernatant and xenografted nude mice sera." in: Chemico-biological interactions, Vol. 245, pp. 39-49, (2016) (PubMed).

Davare, Lal, Peckham, Prajapati, Gultekin, Rubin, Keller: "Secreted meningeal chemokines, but not VEGFA, modulate the migratory properties of medulloblastoma cells." in: Biochemical and biophysical research communications, Vol. 450, Issue 1, pp. 555-60, (2014) (PubMed).

Details zu NRP2

Target: NRP2 (Neuropilin 2 (NRP2))

Andere Bezeichnung: Neuropilin-2

Hintergrund: This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Molekulargewicht: 104831

Gen-ID: 8828

NCBI Accession: NP_003863, NP_061004, NP_957716, NP_957718, NP_957719, NP_958436

UniProt: O60462

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals