Dieses Anti-YOD1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von YOD1 in WB, IF und IHC (p). Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Klon
RB29107
Bindungsspezifität
AA 319-347, C-Term
Homologie
C, Zf
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This YOD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 319-347 amino acids from the C-terminal region of human YOD1.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Bernardi, Williams, Inoue, Schultz, Tsai: "A deubiquitinase negatively regulates retro-translocation of nonubiquitinated substrates." in: Molecular biology of the cell, Vol. 24, Issue 22, pp. 3545-56, (2013) (PubMed).
Target
YOD1
(Ubiquitin Thioesterase OTU1 (YOD1))
Andere Bezeichnung
YOD1
Hintergrund
Deubiquitinating enzymes (DUBs, see MIM 603478) are proteases that specifically cleave ubiquitin (MIM 191339) linkages, negating the action of ubiquitin ligases. DUBA8 belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.[supplied by OMIM].