CNOT8 Antikörper (N-Term)

Produktnummer ABIN655064

Der Kaninchen Polyklonal Anti-CNOT8-Antikörper wurde für WB, IF und IHC (p) validiert. Er ist geeignet, CNOT8 in Proben von Human zu detektieren.

Kurzübersicht für CNOT8 Antikörper (N-Term) (ABIN655064)

Target: CNOT8 (CCR4-NOT Transcription Complex, Subunit 8 (CNOT8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CNOT8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB18739

Produktdetails anti-CNOT8 Antikörper

Bindungsspezifität: AA 34-61, N-Term

Homologie: B, C, Zf, M, X

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CAF-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-61 amino acids from the N-terminal region of human CAF-1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu CNOT8

Target: CNOT8 (CCR4-NOT Transcription Complex, Subunit 8 (CNOT8))

Andere Bezeichnung: CAF-1

Hintergrund: The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs. Alternate splicing of this gene results in two transcript variants encoding different isoforms.

Molekulargewicht: 32745

Gen-ID: 29883

NCBI Accession: NP_037486, NP_473367

UniProt: Q9UIV1