BCLAF1 Antikörper (C-Term)

Produktnummer ABIN654941

Der Kaninchen-Polyklonal Anti-BCLAF1-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet zum Nachweis von BCLAF1 in Proben aus Human. }

Kurzübersicht für BCLAF1 Antikörper (C-Term) (ABIN654941)

Target: BCLAF1 (BCL2-Associated Transcription Factor 1 (BCLAF1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCLAF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB25182

Produktdetails anti-BCLAF1 Antikörper

Bindungsspezifität: AA 658-687, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This BCLAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 658-687 amino acids from the C-terminal region of human BCLAF1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu BCLAF1

Target: BCLAF1 (BCL2-Associated Transcription Factor 1 (BCLAF1))

Andere Bezeichnung: BCLAF1

Hintergrund: This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 106122

Gen-ID: 9774

NCBI Accession: NP_001070908, NP_001070909, NP_055554

UniProt: Q9NYF8

Pathways: Positive Regulation of Response to DNA Damage Stimulus