HYAL2 Antikörper (C-Term)

Produktnummer ABIN654687

Dieses Anti-HYAL2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HYAL2 in WB, FACS und IHC (p). Geeignet für Human.

Kurzübersicht für HYAL2 Antikörper (C-Term) (ABIN654687)

Target: HYAL2 (Hyaluronidase-2 (HYAL2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HYAL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB24065

Produktdetails anti-HYAL2 Antikörper

Bindungsspezifität: AA 385-412, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HYAL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 385-412 amino acids from the C-terminal region of human HYAL2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu HYAL2

Target: HYAL2 (Hyaluronidase-2 (HYAL2))

Andere Bezeichnung: HYAL2

Hintergrund: This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.

Molekulargewicht: 53860

Gen-ID: 8692

NCBI Accession: NP_003764, NP_149348

UniProt: Q12891

Pathways: Transition Metal Ion Homeostasis, Glycosaminoglycan Metabolic Process