NCALD Antikörper (C-Term)

Produktnummer ABIN654452

Der Kaninchen Polyklonal Anti-NCALD-Antikörper wurde für WB validiert. Er ist geeignet, NCALD in Proben von Human und Maus zu detektieren.

Kurzübersicht für NCALD Antikörper (C-Term) (ABIN654452)

Target: NCALD (Neurocalcin delta (NCALD))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCALD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB22143

Produktdetails anti-NCALD Antikörper

Bindungsspezifität: AA 147-174, C-Term

Homologie: B, Pig, Rat, C, Pr, X

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NCALD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-174 amino acids from the C-terminal region of human NCALD.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu NCALD

Target: NCALD (Neurocalcin delta (NCALD))

Andere Bezeichnung: NCALD

Hintergrund: NCALD encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels, however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein, additional variants may exist but their biological validity has not been determined.

Molekulargewicht: 22245

Gen-ID: 83988

NCBI Accession: NP_001035714, NP_001035715, NP_001035716, NP_001035717, NP_001035718, NP_001035719, NP_001035720, NP_114430

UniProt: P61601