ALOXE3 Antikörper (AA 223-252)

Produktnummer ABIN654408

Dieses Anti-ALOXE3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ALOXE3 in WB und IHC (p). Geeignet für Human.

Kurzübersicht für ALOXE3 Antikörper (AA 223-252) (ABIN654408)

Target: ALOXE3 (Arachidonate Lipoxygenase 3 (ALOXE3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALOXE3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB17172

Produktdetails anti-ALOXE3 Antikörper

Bindungsspezifität: AA 223-252

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ALOXE3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-252 amino acids from the Central region of human ALOXE3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P-Leica: 1:500. IHC-P-Leica: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu ALOXE3

Target: ALOXE3 (Arachidonate Lipoxygenase 3 (ALOXE3))

Andere Bezeichnung: ALOXE3

Hintergrund: ALOXE3 is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin.

Molekulargewicht: 80543

Gen-ID: 59344

NCBI Accession: NP_001159432, NP_067641

UniProt: Q9BYJ1

Pathways: Cell-Cell Junction Organization