Der Kaninchen Polyklonal anti-GGTLC2 Antikörper (Klon RB24615) (ABIN654174) detektiert spezifisch GGTLC2 in WB, FACS und IHC (p).
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This GGTLC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-154 amino acids from the Central region of human GGTLC2.
Gamma-glutamyltransferase-1 (GGT1, MIM 612346) is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. Autocatalytic cleavage of the GGT1 precursor polypeptide produces a heavy chain and a light chain that associate with each other to form the functional enzyme. Light chain-only GGTs, such as GGTLC2, contain a region corresponding to the GGT1 light chain, but they lack the membrane-anchoring heavy chain region (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM].