AMH Antikörper (AA 424-451)

Produktnummer ABIN653897

Der Kaninchen Polyklonal Anti-AMH-Antikörper wurde für WB, FACS und IHC (p) validiert. Er ist geeignet, AMH in Proben von Human und Maus zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für AMH Antikörper (AA 424-451) (ABIN653897)

Target: AMH (Anti-Mullerian Hormone (AMH))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AMH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-AMH Antikörper

Bindungsspezifität: AA 424-451

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This AMH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 424-451 amino acids of human AMH.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000-1:2000. IHC-P: 1:25. FC: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-AMH Antikörper (ABIN653897)

Jin, Won, Park, Lee, Park, Bae: "FOXL2 Is an Essential Activator of SF-1-Induced Transcriptional Regulation of Anti-Müllerian Hormone in Human Granulosa Cells." in: PLoS ONE, Vol. 11, Issue 7, pp. e0159112, (2017) (PubMed).

Park, Suh, Lee, Bae: "Positive cross talk between FOXL2 and antimüllerian hormone regulates ovarian reserve." in: Fertility and sterility, (2014) (PubMed).

Details zu AMH

Target: AMH (Anti-Mullerian Hormone (AMH))

Andere Bezeichnung: AMH

Hintergrund: Anti mullerian hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140kD disulphide linked precursor that is cleaved to release the mature 30kD homodimer. Originally classified as a foetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.

Molekulargewicht: 59195

Gen-ID: 268

NCBI Accession: NP_000470

UniProt: P03971

Pathways: Negative Regulation of Hormone Secretion