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PYCR1 Antikörper (C-Term)

PYCR1 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB24671 unconjugated
Produktnummer ABIN653849
  • Target Alle PYCR1 Antikörper anzeigen
    PYCR1 (Pyrroline-5-Carboxylate Reductase 1 (PYCR1))
    Bindungsspezifität
    • 9
    • 9
    • 6
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    AA 291-319, C-Term
    Reaktivität
    • 40
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 38
    • 2
    Kaninchen
    Klonalität
    • 40
    Polyklonal
    Konjugat
    • 21
    • 5
    • 5
    • 5
    • 2
    • 2
    Dieser PYCR1 Antikörper ist unkonjugiert
    Applikation
    • 31
    • 24
    • 22
    • 14
    • 6
    • 5
    • 3
    • 2
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PYCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-319 amino acids from the C-terminal region of human PYCR1.
    Klon
    RB24671
    Isotyp
    IgG
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Zeng, Zhu, Liao, Zhuo, Yang, Wu, Wang: "Knockdown of PYCR1 inhibits cell proliferation and colony formation via cell cycle arrest and apoptosis in prostate cancer." in: Medical oncology (Northwood, London, England), Vol. 34, Issue 2, pp. 27, (2017) (PubMed).

  • Target
    PYCR1 (Pyrroline-5-Carboxylate Reductase 1 (PYCR1))
    Andere Bezeichnung
    PYCR1 (PYCR1 Produkte)
    Synonyme
    arcl2b antikoerper, p5c antikoerper, p5cr antikoerper, pig45 antikoerper, pp222 antikoerper, pro3 antikoerper, pycr antikoerper, ARCL2B antikoerper, ARCL3B antikoerper, P5C antikoerper, P5CR antikoerper, PIG45 antikoerper, PP222 antikoerper, PRO3 antikoerper, PYCR antikoerper, zgc:73112 antikoerper, pyrroline-5-carboxylate reductase family, member 1 L homeolog antikoerper, pyrroline-5-carboxylate reductase 1 antikoerper, pyrroline-5-carboxylate reductase 1a antikoerper, pycr1.L antikoerper, PYCR1 antikoerper, Pycr1 antikoerper, pycr1a antikoerper
    Hintergrund
    This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion.
    Molekulargewicht
    33361
    Gen-ID
    5831
    NCBI Accession
    NP_001269209, NP_001269210, NP_008838, NP_722546
    UniProt
    P32322
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