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PYCR1 Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-PYCR1-Antikörper wurde für WB, FACS und IHC (p) validiert. Er ist geeignet, PYCR1 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.
Produktnummer ABIN653849

Kurzübersicht für PYCR1 Antikörper (C-Term) (ABIN653849)

Target

Alle PYCR1 Antikörper anzeigen
PYCR1 (Pyrroline-5-Carboxylate Reductase 1 (PYCR1))

Reaktivität

  • 35
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 33
  • 2
Kaninchen

Klonalität

  • 35
Polyklonal

Konjugat

  • 21
  • 4
  • 4
  • 4
  • 1
  • 1
Dieser PYCR1 Antikörper ist unkonjugiert

Applikation

  • 27
  • 20
  • 17
  • 11
  • 7
  • 5
  • 3
  • 3
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

RB24671
  • Bindungsspezifität

    • 9
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 291-319, C-Term

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This PYCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-319 amino acids from the C-terminal region of human PYCR1.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Zeng, Zhu, Liao, Zhuo, Yang, Wu, Wang: "Knockdown of PYCR1 inhibits cell proliferation and colony formation via cell cycle arrest and apoptosis in prostate cancer." in: Medical oncology (Northwood, London, England), Vol. 34, Issue 2, pp. 27, (2017) (PubMed).

  • Target

    PYCR1 (Pyrroline-5-Carboxylate Reductase 1 (PYCR1))

    Andere Bezeichnung

    PYCR1

    Hintergrund

    This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion.

    Molekulargewicht

    33361

    Gen-ID

    5831

    NCBI Accession

    NP_001269209, NP_001269210, NP_008838, NP_722546

    UniProt

    P32322
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