Uroplakin 1B Antikörper (AA 159-188)

Produktnummer ABIN653680

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Uroplakin 1B in WB, FACS und IHC (p). Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für Uroplakin 1B Antikörper (AA 159-188) (ABIN653680)

Target: Uroplakin 1B (UPK1B)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Uroplakin 1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB24302

Produktdetails anti-Uroplakin 1B Antikörper

Bindungsspezifität: AA 159-188

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This UPK1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-188 amino acids from the Central region of human UPK1B.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu Uroplakin 1B

Target: Uroplakin 1B (UPK1B)

Andere Bezeichnung: UPK1B

Hintergrund: UPK1B is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.

Molekulargewicht: 29643

Gen-ID: 7348

NCBI Accession: NP_008883

UniProt: O75841