COX6A2 Antikörper (AA 37-66)

Produktnummer ABIN653569

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch COX6A2 in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.Es wurde in 1 Publikation zitiert.

Kurzübersicht für COX6A2 Antikörper (AA 37-66) (ABIN653569)

Target: COX6A2 (Cytochrome C Oxidase Subunit VIa Polypeptide 2 (COX6A2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COX6A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB23260

Produktdetails anti-COX6A2 Antikörper

Bindungsspezifität: AA 37-66

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This COX6A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the Central region of human COX6A2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. IHC-P: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-COX6A2 Antikörper (ABIN653569)

Boczonadi, Giunta, Lane, Tulinius, Schara, Horvath: "Investigating the role of the physiological isoform switch of cytochrome c oxidase subunits in reversible mitochondrial disease." in: The international journal of biochemistry & cell biology, (2015) (PubMed).

Details zu COX6A2

Target: COX6A2 (Cytochrome C Oxidase Subunit VIa Polypeptide 2 (COX6A2))

Andere Bezeichnung: COX6A2

Hintergrund: Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (heart/muscle isoform) of subunit VIa, and polypeptide 2 is present only in striated muscles. Polypeptide 1 (liver isoform) of subunit VIa is encoded by a different gene, and is found in all non-muscle tissues. These two polypeptides share 66 % amino acid sequence identity.

Molekulargewicht: 10815

Gen-ID: 1339

NCBI Accession: NP_005196

UniProt: Q02221