GLDC Antikörper (N-Term)

Produktnummer ABIN653448

Dieses Anti-GLDC-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GLDC in WB. Geeignet für Human und Maus.

Kurzübersicht für GLDC Antikörper (N-Term) (ABIN653448)

Target: GLDC (Glycine Dehydrogenase (GLDC))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLDC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB23981

Produktdetails anti-GLDC Antikörper

Bindungsspezifität: AA 49-77, N-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GLDC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-77 amino acids from the N-terminal region of human GLDC.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu GLDC

Target: GLDC (Glycine Dehydrogenase (GLDC))

Andere Bezeichnung: GLDC

Hintergrund: Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).

Molekulargewicht: 112730

Gen-ID: 2731

NCBI Accession: NP_000161

UniProt: P23378