GINS1 Antikörper (N-Term)

Produktnummer ABIN653447

Der Kaninchen Polyklonal Anti-GINS1-Antikörper wurde für WB validiert. Er ist geeignet, GINS1 in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für GINS1 Antikörper (N-Term) (ABIN653447)

Target: GINS1 (GINS Complex Subunit 1 (Psf1 Homolog) (GINS1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GINS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB23977

Produktdetails anti-GINS1 Antikörper

Bindungsspezifität: AA 1-30, N-Term

Homologie: M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GINS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GINS1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-GINS1 Antikörper (ABIN653447)

Kang, Farina, Bermudez, Tappin, Du, Galal, Hurwitz: "Interaction between human Ctf4 and the Cdc45/Mcm2-7/GINS (CMG) replicative helicase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 49, pp. 19760-5, (2013) (PubMed).

Kang, Galal, Farina, Tappin, Hurwitz: "Properties of the human Cdc45/Mcm2-7/GINS helicase complex and its action with DNA polymerase epsilon in rolling circle DNA synthesis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 16, pp. 6042-7, (2012) (PubMed).

Details zu GINS1

Target: GINS1 (GINS Complex Subunit 1 (Psf1 Homolog) (GINS1))

Andere Bezeichnung: GINS1

Hintergrund: The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4, MIM 610611), Psf1, Psf2 (GINS2, MIM 610609), and Psf3 (GINS3, MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]).

Molekulargewicht: 22988

Gen-ID: 9837

NCBI Accession: NP_066545

UniProt: Q14691

Pathways: DNA Replication, Synthesis of DNA