Nyctalopin Antikörper (N-Term)

Produktnummer ABIN653436

Der Kaninchen Polyklonal anti-Nyctalopin Antikörper (Klon RB23621) (ABIN653436) detektiert spezifisch Nyctalopin in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Nyctalopin Antikörper (N-Term) (ABIN653436)

Target: Nyctalopin (NYX)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Nyctalopin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB23621

Produktdetails anti-Nyctalopin Antikörper

Bindungsspezifität: AA 53-80, N-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NYX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-80 amino acids from the N-terminal region of human NYX.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu Nyctalopin

Target: Nyctalopin (NYX)

Andere Bezeichnung: NYX

Hintergrund: The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB. [provided by RefSeq].

Molekulargewicht: 52000

Gen-ID: 60506

NCBI Accession: NP_072089

UniProt: Q9GZU5