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Nyctalopin Antikörper (N-Term)

Dieses Anti-Nyctalopin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Nyctalopin in WB. Geeignet für Human.
Produktnummer ABIN653436

Kurzübersicht für Nyctalopin Antikörper (N-Term) (ABIN653436)

Target

Alle Nyctalopin (NYX) Antikörper anzeigen
Nyctalopin (NYX)

Reaktivität

  • 11
  • 1
Human

Wirt

  • 11
Kaninchen

Klonalität

  • 11
Polyklonal

Konjugat

  • 6
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Nyctalopin Antikörper ist unkonjugiert

Applikation

  • 11
  • 9
  • 2
  • 1
Western Blotting (WB)

Klon

RB23621
  • Bindungsspezifität

    • 7
    • 2
    • 2
    • 2
    AA 53-80, N-Term

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This NYX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-80 amino acids from the N-terminal region of human NYX.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Target

    Nyctalopin (NYX)

    Andere Bezeichnung

    NYX

    Hintergrund

    The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB. [provided by RefSeq].

    Molekulargewicht

    52000

    Gen-ID

    60506

    NCBI Accession

    NP_072089

    UniProt

    Q9GZU5
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