F-Box Protein 3 Antikörper (C-Term)
Kurzübersicht für F-Box Protein 3 Antikörper (C-Term) (ABIN2842715)
Target
Alle F-Box Protein 3 (FBXO3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 395-422, C-Term
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Homologie
- M
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This FBXO3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-422 amino acids from the C-terminal region of human FBXO3.
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Isotyp
- Ig Fraction
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Applikationshinweise
- WB: 1:1000. FC: 1:10~50
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Haltbarkeit
- 6 months
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: "Targeted inhibition of the COP9 signalosome for treatment of cancer." in: Nature communications, Vol. 7, pp. 13166, (2018) (PubMed).
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: "Targeted inhibition of the COP9 signalosome for treatment of cancer." in: Nature communications, Vol. 7, pp. 13166, (2018) (PubMed).
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- F-Box Protein 3 (FBXO3)
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Andere Bezeichnung
- FBXO3
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Hintergrund
- FBXO3 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs.
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Molekulargewicht
- 54561
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Gen-ID
- 26273
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NCBI Accession
- NP_036307, NP_208385
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UniProt
- Q9UK99
Target
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