Der Kaninchen Polyklonal Anti-CBY1/PGEA1-Antikörper wurde für WB, IHC (p) und FACS validiert. Er ist geeignet, CBY1/PGEA1 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This HRIHFB2025 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the C-terminal region of human HRIHFB2025.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Yamano, Uzawa, Saito, Nakashima, Kasamatsu, Koike, Kouzu, Shinozuka, Nakatani, Negoro, Fujita, Tanzawa: "Identification of cisplatin-resistance related genes in head and neck squamous cell carcinoma." in: International journal of cancer. Journal international du cancer, Vol. 126, Issue 2, pp. 437-49, (2009) (PubMed).
Target
CBY1/PGEA1 (CBY1)
(Chibby Homolog 1 (CBY1))
Andere Bezeichnung
HRIHFB2025
Hintergrund
Inhibits the Wnt/Wingless pathway by binding to beta catenin and inhibiting beta catenin mediated transcriptional activation by competing with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin 2/PKD2 and possibly of other intracellular proteins.