Mu Opioid Receptor 1 Antikörper (AA 161-187)

Produktnummer ABIN653074

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Mu Opioid Receptor 1 in WB, IHC (p) und FACS. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für Mu Opioid Receptor 1 Antikörper (AA 161-187) (ABIN653074)

Target: Mu Opioid Receptor 1 (OPRM1) (Opioid Receptor, mu 1 (OPRM1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Mu Opioid Receptor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Klon: RB22405

Produktdetails anti-Mu Opioid Receptor 1 Antikörper

Bindungsspezifität: AA 161-187

Homologie: Pr, Pig, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This OPRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-187 amino acids from the Central region of human OPRM1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:500. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu Mu Opioid Receptor 1

Target: Mu Opioid Receptor 1 (OPRM1) (Opioid Receptor, mu 1 (OPRM1))

Andere Bezeichnung: OPRM1

Hintergrund: OPRM1 is the mu opioid receptor, which is the primary site of action for the most commonly used opioids, including morphine, heroin, fentanyl, and methadone. It is also the primary receptor for endogenous opioid peptides beta-endorphin (see POMC, MIM 176830) and the enkephalins (see PENK, MIM 131330). The OPRM1 receptor is a membrane of the G protein-coupled receptor family (Bond et al., 1998 [PubMed 9689128]). There are at least 3 types of opioid receptors, mu, kappa (OPRK1, MIM 165196), and delta, each with a distinct pharmacologic profile.

Molekulargewicht: 44779

Gen-ID: 4988

NCBI Accession: NP_000905, NP_001008503, NP_001008504, NP_001008505, NP_001138751, NP_001138752, NP_001138753, NP_001138754, NP_001138755, NP_001138756, NP_001138757, NP_001138758, NP_001138759

UniProt: P35372

Pathways: cAMP Metabolic Process, Synaptic Membrane