Denatured ATG1 Antikörper

Produktnummer ABIN653062

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch in FACS, IHC (p) und WB. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für Denatured ATG1 Antikörper (ABIN653062)

Target: Denatured ATG1

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Klon: RB17499

Produktdetails

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This denatured ATG1 antibody is generated from rabbits immunized with a denatured human ATG1 recombinant protein.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: Denatured ATG1

Hintergrund: ULK1 is involved in autophagy. It is required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex (By similarity). Phosphorylates ATG13/KIAA0652. It is involved in axon growth (By similarity) and plays an essential role in neurite extension of cerebellar granule cells (By similarity).

Molekulargewicht: 112631

Gen-ID: 8408

NCBI Accession: NP_003556

UniProt: O75385