GCLM Antikörper (C-Term)

Produktnummer ABIN653046

Dieses Anti-GCLM-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GCLM in WB, IF, FACS und IHC (p). Geeignet für Human und Maus. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für GCLM Antikörper (C-Term) (ABIN653046)

Target: GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GCLM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB22980

Produktdetails anti-GCLM Antikörper

Bindungsspezifität: AA 246-274, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GCLM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 246-274 amino acids from the C-terminal region of human GCLM.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000. WB: 1:1000. WB: 1:8000. IHC-P: 1:25. IHC-P: 1:25. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-GCLM Antikörper (ABIN653046)

Chen, Jiang, Hu, Zhang: "The protective role of resveratrol in the sodium arsenite-induced oxidative damage via modulation of intracellular GSH homeostasis." in: Biological trace element research, Vol. 155, Issue 1, pp. 119-31, (2014) (PubMed).

Details zu GCLM

Target: GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))

Andere Bezeichnung: GCLM

Hintergrund: GCLM known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.

Molekulargewicht: 30727

Gen-ID: 2730

NCBI Accession: NP_002052

UniProt: P48507