NEK3 Antikörper (AA 331-361)

Produktnummer ABIN652427

Der Kaninchen Polyklonal Anti-NEK3-Antikörper wurde für WB validiert. Er ist geeignet, NEK3 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für NEK3 Antikörper (AA 331-361) (ABIN652427)

Target: NEK3 (NIMA related kinase 3 (NEK3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NEK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB2961

Produktdetails anti-NEK3 Antikörper

Bindungsspezifität: AA 331-361

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NEK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-361 amino acids from the Central region of human NEK3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. WB: 1:2000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-NEK3 Antikörper (ABIN652427)

McHale, Tomaszewski, Puthiyaveettil, Livolsi, Clevenger: "Altered expression of prolactin receptor-associated signaling proteins in human breast carcinoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 21, Issue 5, pp. 565-71, (2008) (PubMed).

Details zu NEK3

Target: NEK3 (NIMA related kinase 3 (NEK3))

Andere Bezeichnung: NEK3

Hintergrund: In Aspergillus nidulans, lack of the serine/threonine kinase NimA (never in mitosis A) results in cell cycle arrest in G2, while overexpression causes the premature onset of mitotic events. NEK3 is similar in sequence to the Aspergillus nidulans protein and may therefore play a role in mitotic regulation. However, the encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm.

Molekulargewicht: 57705

NCBI Accession: NP_001139571, NP_002489, NP_689933

UniProt: P51956