AAK1 Antikörper (N-Term)

Produktnummer ABIN652404

Der Kaninchen Polyklonal anti-AAK1 Antikörper (Klon RB16487) (ABIN652404) detektiert spezifisch AAK1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für AAK1 Antikörper (N-Term) (ABIN652404)

Target: AAK1 (AP2 associated kinase 1 (AAK1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AAK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB16487

Produktdetails anti-AAK1 Antikörper

Bindungsspezifität: AA 186-216, N-Term

Homologie: B, Pig

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This AAK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-216 amino acids from the N-terminal region of human AAK1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu AAK1

Target: AAK1 (AP2 associated kinase 1 (AAK1))

Andere Bezeichnung: AAK1

Hintergrund: Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. AAK1 is a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin.

Molekulargewicht: 103885

Gen-ID: 22848

NCBI Accession: NP_055726

UniProt: Q2M2I8