BRDT Antikörper (N-Term)

Produktnummer ABIN652290

Dieses Anti-BRDT-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BRDT in WB. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für BRDT Antikörper (N-Term) (ABIN652290)

Target: BRDT (Bromodomain, Testis-Specific (BRDT))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRDT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB8492

Produktdetails anti-BRDT Antikörper

Bindungsspezifität: AA 1-30, N-Term

Homologie: Pr

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This BRDT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human BRDT.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-BRDT Antikörper (ABIN652290)

Li, Sha, Wang, Li, Wang, Kee, Wang: "Whole-exome sequencing identified a homozygous BRDT mutation in a patient with acephalic spermatozoa." in: Oncotarget, Vol. 8, Issue 12, pp. 19914-19922, (2017) (PubMed).

Details zu BRDT

Target: BRDT (Bromodomain, Testis-Specific (BRDT))

Andere Bezeichnung: BRDT

Hintergrund: BRDT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues), characteristic of proteins that undergo rapid intracellular degradation. The bromodomain is found in proteins that regulate transcription. Two transcript variants encoding the same protein have been found for this gene. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.

Molekulargewicht: 107954

Gen-ID: 676

NCBI Accession: NP_001229734, NP_001229735, NP_001229736, NP_001229737, NP_001229739, NP_001717, NP_997072

UniProt: Q58F21